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Thorne Methyl-Guard Plus Active Folate 5-MTHF – 90 Capsules
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Thorne Methyl-Guard Plus Active Folate 5-MTHF – 90 Capsules
  • Thorne Methyl-Guard Plus Active Folate 5-MTHF – 90 Capsules
  • Thorne Methyl-Guard Plus Active Folate 5-MTHF – 90 Capsules
  • Thorne Methyl-Guard Plus Active Folate 5-MTHF – 90 Capsules
  • Thorne Methyl-Guard Plus Active Folate 5-MTHF – 90 Capsules
  • Thorne Methyl-Guard Plus Active Folate 5-MTHF – 90 Capsules
Thorne Methyl-Guard Plus Active Folate 5-MTHF – 90 Capsules

Thorne Methyl-Guard Plus Active Folate 5-MTHF – 90 Capsules

$58.00 $62.00

2 reviews

All Skin Types, Including Sensitive.

Thorne Methyl-Guard Plus is an active B-vitamin formula built around 5-MTHF (the bioactive form of folate) alongside methylated B2, B6, and B12, plus betaine (trimethylglycine). It's designed to deliver methyl donors the body can use directly, without relying on the conversion steps that standard folic acid and cyanocobalamin require. The bottle contains 90 capsules.
Key Ingredients
  • L-5-MTHF (Active Folate): the already-active form of folate, which bypasses the enzymatic conversion some people process less efficiently.
  • Riboflavin 5'-Phosphate (B2) and Pyridoxal 5'-Phosphate (B6): bioactive, tissue-ready forms of these methylation-supporting B vitamins.
  • Methylcobalamin (B12): the active, methylated form of vitamin B12.
  • Betaine Anhydrous (TMG): an additional methyl donor that supports the broader methylation cycle.
Key Benefits
  • Formulated to support healthy methylation*
  • May help support already-healthy homocysteine levels*
  • Gluten-free, dairy-free, and soy-free capsule formula
How To Use

Adults looking for targeted methylation and active B-vitamin support, including those who prefer methylated folate and B12 over standard folic acid and cyanocobalamin forms. This statement has not been evaluated by the FDA and this product is not intended to diagnose, treat, cure, or prevent any disease.

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Frequently Asked Questions

  • Most of our products are formulated to be gentle. However, we always recommend a patch test before full application, especially for sensitive skin.
  • Results vary depending on skin type and consistency of use. Many users notice improvements within 2–4 weeks of regular application.
  • Yes, unless otherwise stated. Follow the recommended usage instructions on the product page for best results.
  • Yes. This product is designed to work within a skincare routine. If using active ingredients, introduce gradually and monitor skin response.
  • If you are pregnant or breastfeeding, consult your healthcare professional before introducing new skincare products.
  • Most of our formulations are non-comedogenic. Individual reactions vary, so discontinue use if irritation occurs.
  • Yes. Apply in the recommended order within your routine. Allow the product to absorb fully before layering.
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